In a speech that lasted roughly 35 minutes, President Trump called several people to the microphone for brief statements, including the family of an overdose victim, an immigration agent, the manufacturer of Narcan®, and HHS Secretary Alex Azar. He spoke of increasing penalties for drug traffickers (including the death penalty), and he cited "sanctuary cities" like Lawrence, Massachusetts and Boston as sources of "fentanol" being sold in southern New Hampshire.

The president also applauded the manufacturers of naloxone for providing the "life-saving" opioid antagonist to high schools, colleges, and first responders at no charge. We need, he said, to work on the problem of relapse. Trump also promised to work on lowering drug prices, including the price of naloxone, and he spoke in support of "right to try" legislation.

President Trump finished with a call for "trust in our citizens, pride in our country, and faith in our god," stating that with those, "We will not fail" in our fight against the opioid crisis.